Extensional flow of blood analog solutions in microfluidic devices
نویسندگان
چکیده
منابع مشابه
Extensional flow of blood analog solutions in microfluidic devices.
In this study, we show the importance of extensional rheology, in addition to the shear rheology, in the choice of blood analog solutions intended to be used in vitro for mimicking the microcirculatory system. For this purpose, we compare the flow of a Newtonian fluid and two well-established viscoelastic blood analog polymer solutions through microfluidic channels containing both hyperbolic an...
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CEFT, Departmento de Engenharia Química, Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal Department of Mechanical Engineering, MIT, 77 Massachusetts Avenue, Cambridge , MA 02139-4307, USA Department of Chemical and Biomolecular Engineering, The University of Melbourne, VIC 3010, Australia Email: [email protected], [email protected], [email protected], mm...
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We utilize a recently developed microfluidic device, the Optimized Shape Cross-slot Extensional Rheometer (OSCER), to study the elongational flow behavior and rheological properties of hyaluronic acid (HA) solutions representative of the synovial fluid (SF) found in the knee joint. The OSCER geometry is a stagnation point device that imposes a planar extensional flow with a homogenous extension...
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A precision-machined cross-slot flow geometry with a shape that has been optimized by numerical simulation of the fluid kinematics is fabricated and used to measure the extensional viscosity of a dilute polymer solution. Full-field birefringence microscopy is used to monitor the evolution and growth of macromolecular anisotropy along the stagnation point streamline, and we observe the formation...
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ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2011
ISSN: 1932-1058
DOI: 10.1063/1.3567888